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Spaghetti Squash Casserole

Easy, satisfying, and good for your body and soul: try this awesome spaghetti squash casserole!

This is spaghetti squash casserole. There is melted cheese and red pepper flakes on top of diced peppers and onions with ground turkey.

Spaghetti squash casserole

Ah, the incredible, edible spaghetti squash. Like coffee cake, it is not the first word that describes what it actually is, but the second: it is squash. Unlike coffee cake, the first word still says something about the physical nature of the thing: when roasted and picked apart, the meat of the squash becomes this stranded, fibrous stuff that’s kind of like spaghetti.

This makes it really great for things that spaghetti is great for, and sometimes even better because the rind is a built-in container, as in my recipe for spaghetti squash boats.

Sometimes, you have to step up your squash game and jump from boat to casserole dish—as a newly-returned Midwesterner, this is practically my duty. The results are delicious, I assure you.

Spaghetti squash casserole recipe

This casserole is a one-stop shop for nutritious goodness. You’ve got the protein, the fiber, the flavor—everything you need to succeed and be a hit with your friends and family (or just yourself! I don’t know your situation)!

This casserole stands out in the wide world of casseroles because it fills you up without making you feel like you drank out of a cement truck afterwards. It keeps you fuller longer (that’s that squash!), which is good because you’ll want this to last all week long.

Spaghetti squash casserole ingredients

Here’s what we’ve got going on for ingredients:

You’re going to start be microwaving the squash for a few minutes before you actually cut into it. It’s going to make the dreaded slicing-in-half step a pleasant experience.

  • spaghetti squash
  • ground turkey (93% lean)
  • mozzarella cheese (shredded)
  • bell peppers
  • onion
  • diced tomatoes
  • garlic
  • olive oil
  • red pepper flakes
  • onion powder
  • salt and pepper

Everything’s going to end up in the same dish, too, which is pretty convenient.

This is a skillet of some of the ingredients for spaghetti squash casserole. There are diced bell peppers and onion on the right side of the skillet. The left side of the skillet is a chunk of raw ground turkey.

How to make spaghetti squash casserole

Some are intimidated by mastering the whole spaghetti squash prep situation, but I promise you it’s a breeze, especially if you use the technique this recipe recommends.

Here’s the whole thing:

  • Start by preparing the spaghetti squash. Use a fork to poke a few holes in the spaghetti squash where you will cut it in half (lengthwise). Microwave the entire squash for about 5 minutes. Use a large, sharp knife to cut the squash in half. Use a spoon to scoop out the seeds. Spray each half of the spaghetti squash with cooking oil (or drizzle with olive oil). Sprinkle each side with salt and pepper. Place the spaghetti squash halves face side down on a greased baking sheet. Bake at 400 for 30-40 mins until tender and lightly brown. Take the squash out of the oven, let cool, and use forks to shred the squash into strands. Place the shredded squash in a bowl and set aside.
  • Heat a large skillet over medium-high heat. Add olive oil.
  • Add the pepper, onion, garlic, and ground turkey to the skillet. Sprinkle with seasonings. Cook for about 10 minutes, until the meat is no longer pink.
  • Add the can of tomatoes to the skillet. Cook for another 3-5 minutes.
  • Scoop in the spaghetti squash and ½ of the cheese. Mix well.
  • Use a slotted spoon or tongs to add the casserole mixture to a greased casserole dish. (The slotted spoon is to leave behind the juices. Adding some of the juice is no big deal.)
  • Sprinkle remaining cheese on top of the casserole.
  • Bake at 350 for 20 minutes or the cheese is melted.
  • Top with additional red pepper flakes for a kick. Enjoy!
This is a dish of spaghetti squash casserole. There is dish filled with melted cheese on top of peppers, onions, and ground turkey.

How to reheat this casserole

The beauty of this spaghetti squash casserole is that you can reheat the whole casserole dish at once (in the oven) OR just go ahead and take out single servings at a time and pop them in the microwave.

When reheating in the oven, you might cover it in aluminum foil to prevent the dish from drying out.

This is a skillet of ingredients for spaghetti squash casserole. The skillet is filled with diced peppers, onions, and cooked ground turkey.

Is spaghetti squash healthy?

Nothing is automatically going to be healthy on its own, but spaghetti squash itself is pretty great from a nutritional standpoint. Low in fat and carbs, it’s a great replacement for pasta in many contexts.

As a casserole, this dish can absolutely be part of a thoughtful nutrition plan and help keep you fueled in your day-to-day.

This is a casserole dish with the uncooked spaghetti squash casserole. There are diced peppers, onions, tomatoes, and ground turkey covered in shredded white mozzarella cheese.

How do you keep squash casserole from getting watery?

Because of the liquid contained in spaghetti squash, some people run into issues with it being a bit watery. In the context of this casserole, I don’t notice that being so much of a problem—likely because other ingredients are absorbing the moisture!

That said, I’ve heard that salting it and letting it sit for a while can draw out some of the excess moisture. To be honest, I haven’t tried that for this recipe because I haven’t needed to do it to achieve great results. If you give that technique a go, let me know how it works for you!

Looking for something similar?

Why not try one of these Jordo’s World staples:

This is a dish of spaghetti squash casserole. There is dish filled with melted cheese on top of peppers, onions, and ground turkey.
This is spaghetti squash casserole. There is melted cheese and red pepper flakes on top of diced peppers and onions with ground turkey.
Print Recipe
5 from 6 votes

Spaghetti Squash Casserole

Easy, satisfying, and good for your body and soul: try this awesome spaghetti squash casserole!
Prep Time1 hr
Cook Time20 mins
Course: Main Course
Cuisine: American
Keyword: casserole, spaghetti squash
Servings: 6
Calories: 274kcal
Author: Jordan Smith

Equipment

  • skillet
  • casserole dish
  • oven

Ingredients

  • 1 spaghetti squash
  • 1 lb ground turkey 93% lean
  • 1 cup mozzarella cheese shredded
  • 2 bell peppers diced
  • 1 medium onion diced
  • 1 can diced tomatoes fire roasted or italian
  • 2 cloves garlic minced
  • 2 tbsp olive oil
  • 1 tsp red pepper flakes
  • 1 tsp onion powder
  • salt and pepper pinch

Instructions

  • Start by preparing the spaghetti squash. Use a fork to poke a few holes in the spaghetti squash where you will cut the it in half (length wise). Microwave the entire squash for about 5 minutes. Use a large, sharp knife to cut the squash in half. Use a spoon to scoop out the seeds. Spray each half of the spaghetti squash with cooking oil (or drizzle with olive oil). Sprinkle each side with salt and pepper. Place the spaghetti squash halves face side down on a greased baking sheet. Bake at 400 for 30-40 mins until tender and lightly brown. Take the squash out of the oven, let cool, and use forks to shred the squash into strands. Place the shredded squash in a bowl and set aside.
  • Heat a large skillet over medium-high heat. Add olive oil.
  • Add the pepper, onion, garlic, and ground turkey to the skillet. Sprinkle with seasonings. Cook for about 10 minutes, until the meat is no longer pink.
    This is a skillet of some of the ingredients for spaghetti squash casserole. There are diced bell peppers and onion on the right side of the skillet. The left side of the skillet is a chunk of raw ground turkey.
  • Add the can of tomatoes to the skillet. Cook for another 3-5 minutes.
    This is a skillet of ingredients for spaghetti squash casserole. The skillet is filled with diced peppers, onions, and cooked ground turkey.
  • Scoop in the spaghetti squash and ½ of the cheese. Mix well.
  • Use a slotted spoon or tongs to add the casserole mixture to a greased casserole dish. (The slotted spoon is to leave behind the juices. Adding some of the juice is no big deal.)
    This is a casserole dish with the uncooked spaghetti squash casserole. There are diced peppers, onions, tomatoes, and ground turkey covered in shredded white mozzarella cheese.
  • Sprinkle remaining cheese on top of the casserole.
  • Bake at 350 for 20 minutes or the cheese is melted.
    This is a dish of spaghetti squash casserole. There is dish filled with melted cheese on top of peppers, onions, and ground turkey.
  • Top with additional red pepper flakes for a kick. Enjoy!
    This is spaghetti squash casserole. There is melted cheese and red pepper flakes on top of diced peppers and onions with ground turkey.

Nutrition

Calories: 274kcal | Carbohydrates: 20g | Protein: 22g | Fat: 15g
Recipe Rating




Jasmyn

Sunday 19th of June 2022

This is a favorite to make ahead and have all week I like to warm it up over a bed of spinach!

Treva

Friday 17th of June 2022

I have made this several times and it’s delicious! I have 5 kiddos and they all take a second serving!

Jasmyn

Friday 17th of June 2022

This is a favorite to make ahead and have for lunch all week. A nice filling portion for the macros.

Jana Parrigon

Monday 6th of December 2021

This was such a great meal. The flavor is robust, and it came together really easily. I cooked the spaghetti squash early in the day, so I just threw it in while adding the ingredients. This was so yummy!

Sharon

Sunday 5th of December 2021

This was easy and delicious! It hit the spot with needing warm comfort food but without all the calories that come from Comfort food.